Journal
E-JOURNAL OF CHEMISTRY
Volume 7, Issue 1, Pages 55-58Publisher
HINDAWI LTD
DOI: 10.1155/2010/604549
Keywords
Synthesis; Isatin; Spiropyrazolines; Spiropyrimidinethione
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Reaction of isatin with acetophenone derivatives gave 3-hydroxy-3-phenacyl oxindole derivatives (II), dehydration of (II) gave 3-phenacylidene-2-indolinone derivatives (III). Condensation of (III) with hydrazine hydrate, phenylhydrazine and phenylthiourea afforded new spiropyrazolines (IV & V) and spiropyrimidinethione (VI) respectively. The structures of the final products were established by physical and spectral means.
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