4.6 Article

Efficacy and Safety of Long-Acting Reversible Contraception

Journal

DRUGS
Volume 71, Issue 8, Pages 969-980

Publisher

ADIS INT LTD
DOI: 10.2165/11591290-000000000-00000

Keywords

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Funding

  1. Midcareer Investigator Award in Women's Health Research [K24 HD01298]
  2. National Center for Research Resources (NCRR) [UL1RR024992]
  3. National Institutes of Health (NIH)
  4. NIH Roadmap for Medical Research
  5. EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT [K24HD001298] Funding Source: NIH RePORTER
  6. NATIONAL CENTER FOR RESEARCH RESOURCES [UL1RR024992] Funding Source: NIH RePORTER

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Long-acting reversible contraception (LA RC) includes intrauterine devices (IUDs) and the subdermal implant. These methods are the most effective reversible methods of contraception, and have the additional advantages of being long-lasting, convenient, well liked by users and cost effective. Compared with other user-dependent methods that increase the risk of noncompliance-related method failure, LARC methods can bring 'typical use' failure rates more in line with 'perfect use' failure rates. LARC methods are 'forgettable'; they are not dependent on compliance with a pill-taking regimen, remembering to change a patch or ring, or coming back to the clinician for an injection. LARC method failure rates rival that of tubal sterilization at < 1% for IUDs and the subdermal implant. For these reasons, we believe that IUDs and implants should be offered as first-line contraception for most women. This article provides a review of the LARC methods that are currently available in the US, including their effectiveness, advantages, disadvantages and contraindications. Additionally, we dispel myths and misconceptions regarding IUDs, and address the barriers to LARC use.

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