4.4 Review

Arylamine N-acetyltransferases: From structure to function

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1

Akane Kawamura et al.

BIOCHEMICAL PHARMACOLOGY (2008)

Article Biochemistry & Molecular Biology

Divergence of cofactor recognition across evolution:: Coenzyme a binding in a prokaryotic arylamine N-acetyltransferase

Elizabeth Fullam et al.

JOURNAL OF MOLECULAR BIOLOGY (2008)

Article Pharmacology & Pharmacy

Current trends in N-acetyltransferase research arising from the 2007 International NAT Workshop

Sotiria Boukouvala et al.

PHARMACOGENOMICS (2008)

Article Biochemistry & Molecular Biology

Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia

Helene Magalon et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2008)

Article Biochemistry & Molecular Biology

Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism

Larissa Wakefield et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Review Biochemistry & Molecular Biology

HECT E3s and human disease

Martin Scheffner et al.

BMC BIOCHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases

Hong Wu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Oncology

Genetic susceptibility for breast cancer: How many more genes to be found?

R. A. Oldenburg et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2007)

Review Public, Environmental & Occupational Health

A meta-analysis of the association of N-acetyltransferase 2 gene (NAT2) variants with breast cancer

Heather M. Ochs-Balcom et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2007)

Article Biochemistry & Molecular Biology

Ocular defects associated with a null mutation in the mouse arylamine N-acetyltransferase 2 gene

Larissa Wakefield et al.

MAMMALIAN GENOME (2007)

Article Multidisciplinary Sciences

A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages

Robert Van der Geize et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Pharmacology & Pharmacy

Computational and experimental analyses of mammalian arylamine N-acetyltransferase structure and function

Jason M. Walraven et al.

DRUG METABOLISM AND DISPOSITION (2007)

Review Biochemistry & Molecular Biology

Arylamine N-acetyltransferases

Edith Sim et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2007)

Article Genetics & Heredity

Orofacial cleft risk is increased with maternal smoking and specific detoxification-gene variants

Min Shi et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2007)

Article Biochemistry & Molecular Biology

Arylamine N-acetyltransferase I

Rodney F. Minchin et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)

Article Pharmacology & Pharmacy

N-acetyltransferase (Nat) 1 and 2 expression in Nat2 knockout mice

Jennifer A. Loehle et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)

Article Oncology

Tobacco smoking, NAT2 acetylation genotype and breast cancer risk

Jolanta Lissowska et al.

INTERNATIONAL JOURNAL OF CANCER (2006)

Article Biochemistry & Molecular Biology

NMR-based model reveals the structural determinants of mammalian arylamine N-acetyltransferase substrate specificity

Naixia Zhang et al.

JOURNAL OF MOLECULAR BIOLOGY (2006)

Article Pharmacology & Pharmacy

Identification and characterization of functional rat arylamine N-acetyltransferase 3:: Comparisons with rat arylamine N-acetyltransferases 1 and 2

Jason M. Walraven et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)

Article Pharmacology & Pharmacy

In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice

K. S. Sugamori et al.

DRUG METABOLISM AND DISPOSITION (2006)

Article Biochemistry & Molecular Biology

Arylamine N-acetyltransferase aggregation and constitutive ubiquitylation

Fen Liu et al.

JOURNAL OF MOLECULAR BIOLOGY (2006)

Article Genetics & Heredity

Loss of function polymorphisms in NAT1 protect against spina bifida

Liselotte E. Jensen et al.

HUMAN GENETICS (2006)

Article Biotechnology & Applied Microbiology

Functional properties of an alternative, tissue-specific promoter for human arylamine N-acetyltransferase 1

David F. Barker et al.

PHARMACOGENETICS AND GENOMICS (2006)

Article Multidisciplinary Sciences

Hsp70 chaperones accelerate protein translocation and the unfolding of stable protein aggregates by entropic pulling

P De los Rios et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Genetics & Heredity

Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes

E Patin et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2006)

Article Biochemistry & Molecular Biology

Characterization of the putative operon containing arylamine N-acetyltransferase (nat) in Mycobacterium bovis BCG

MC Anderton et al.

MOLECULAR MICROBIOLOGY (2006)

Review Chemistry, Medicinal

Structure and mechanism of arylamine N-acetyltransferases

I. M. Westwood et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2006)

Article Microbiology

Mutational and expression analysis of tbnat and its response to isoniazid

C Sholto-Douglas-Vernon et al.

JOURNAL OF MEDICAL MICROBIOLOGY (2005)

Article Multidisciplinary Sciences

An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

LD Miller et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Developmental Biology

The NAT1 C1095A polymorphism, maternal multivitamin use and smoking, and the risk of spina bifida

LE Jensen et al.

BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2005)

Article Multidisciplinary Sciences

Human thiopurine S-methyltransferase pharmacogenetics:: Variant allozyme misfolding and aggresome formation

LW Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Pharmacology & Pharmacy

Structural analysis of the genes for human arylamine N-acetyltransferases and characterisation of alternative transcripts

S Boukouvala et al.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2005)

Article Cell Biology

Arylamine N-acetyltransferase 2 expression in the developing heart

L Wakefield et al.

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2005)

Article Genetics & Heredity

Only low levels of exogenous N-acetyltransferase can be achieved in transgenic mice

W Cao et al.

PHARMACOGENOMICS JOURNAL (2005)

Article Pharmacology & Pharmacy

Arylamine N-acetyltransferases: What we learn from genes and genomes

S Boukouvala et al.

DRUG METABOLISM REVIEWS (2005)

Article Public, Environmental & Occupational Health

Maternal smoking and the risk of orofacial clefts - Susceptibility with NAT1 and NAT2 polymorphisms

EJ Lammer et al.

EPIDEMIOLOGY (2004)

Article Biochemistry & Molecular Biology

Active solubilization and refolding of stable protein aggregates by cooperative unfolding action of individual Hsp70 chaperones

A Ben-Zvi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Active-site alkylation destabilizes human O-6-alkylguanine DNA alkyltransferase

JJ Rasimas et al.

PROTEIN SCIENCE (2004)

Article Developmental Biology

Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for Orofacial clefts

EJ Lammer et al.

BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2004)

Article Biochemistry & Molecular Biology

An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases

EW Brooke et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2003)

Review Cell Biology

How the ubiquitin-proteasome system controls transcription

M Muratani et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)

Article Multidisciplinary Sciences

Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity

H Sakahira et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biotechnology & Applied Microbiology

Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis

DW Hein

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2002)

Article Cell Biology

Cytoplasmic dynein/dynactin mediates the assembly of aggresomes

JA Johnston et al.

CELL MOTILITY AND THE CYTOSKELETON (2002)

Review Multidisciplinary Sciences

Gene expression - Emerging roles of ubiquitin in transcription regulation

RC Conaway et al.

SCIENCE (2002)

Article Biochemistry & Molecular Biology

The COOH terminus of arylamine N-acetyltransferase from Salmonella typhimurium controls enzymic activity

A Mushtaq et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

Gene expression profiling predicts clinical outcome of breast cancer

LJ van't Veer et al.

NATURE (2002)

Review Pharmacology & Pharmacy

The pharmacogenetics of NAT: structural aspects

F Pompeo et al.

PHARMACOGENOMICS (2002)

Article Multidisciplinary Sciences

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

T Sorlie et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biotechnology & Applied Microbiology

N-acetyltransferases, sulfotransferases and heterocyclic amine activation in the breast

JA Williams et al.

PHARMACOGENETICS (2001)

Review Cell Biology

Sumo, ubiquitin's mysterious cousin

S Müller et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)

Review Cell Biology

Aggresomes, inclusion bodies and protein aggregation

RR Kopito

TRENDS IN CELL BIOLOGY (2000)

Review Cell Biology

The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

PK Jackson et al.

TRENDS IN CELL BIOLOGY (2000)

Article Multidisciplinary Sciences

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes

U Schubert et al.

NATURE (2000)

Article Biochemistry & Molecular Biology

Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos

VA Smelt et al.

HUMAN MOLECULAR GENETICS (2000)

Review Biotechnology & Applied Microbiology

Repair of O6-alkylguanine by alkyltransferases

AE Pegg

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2000)