Related references
Note: Only part of the references are listed.Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1
Akane Kawamura et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system
Larissa Wakefield et al.
BIOMARKERS (2008)
Arylamine N-acetyltransferase I expression in breast cancer cell lines:: A potential marker in estrogen receptor-positive tumors
Larissa Wakefield et al.
GENES CHROMOSOMES & CANCER (2008)
Divergence of cofactor recognition across evolution:: Coenzyme a binding in a prokaryotic arylamine N-acetyltransferase
Elizabeth Fullam et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Current trends in N-acetyltransferase research arising from the 2007 International NAT Workshop
Sotiria Boukouvala et al.
PHARMACOGENOMICS (2008)
Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia
Helene Magalon et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2008)
Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism
Larissa Wakefield et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
HECT E3s and human disease
Martin Scheffner et al.
BMC BIOCHEMISTRY (2007)
Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases
Hong Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Tissue expression and genomic sequences of rat N-acetyltransferases rNat1, rNat2, rNat3, and functional characterization of a novel rNat3*2 genetic variant
Jason M. Walraven et al.
TOXICOLOGICAL SCIENCES (2007)
Functional analysis of the human N-acetyltransferase 1 major promoter:: Quantitation of tissue expression and identification of critical sequence elements
Anwar Husain et al.
DRUG METABOLISM AND DISPOSITION (2007)
Genetic susceptibility for breast cancer: How many more genes to be found?
R. A. Oldenburg et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2007)
A meta-analysis of the association of N-acetyltransferase 2 gene (NAT2) variants with breast cancer
Heather M. Ochs-Balcom et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2007)
Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series
Christine Desmedt et al.
CLINICAL CANCER RESEARCH (2007)
Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues
Anwar Husain et al.
DRUG METABOLISM AND DISPOSITION (2007)
Ocular defects associated with a null mutation in the mouse arylamine N-acetyltransferase 2 gene
Larissa Wakefield et al.
MAMMALIAN GENOME (2007)
Description of a novel polymorphic gene encoding for arylamine N-acetyltransferase in the rhesus macaque (Macaca mulatta), a model animal for endometriosis
Giannoulis Fakis et al.
PHARMACOGENETICS AND GENOMICS (2007)
A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages
Robert Van der Geize et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells
Neville J. Butcher et al.
CANCER RESEARCH (2007)
Computational and experimental analyses of mammalian arylamine N-acetyltransferase structure and function
Jason M. Walraven et al.
DRUG METABOLISM AND DISPOSITION (2007)
Arylamine N-acetyltransferases
Edith Sim et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2007)
Orofacial cleft risk is increased with maternal smoking and specific detoxification-gene variants
Min Shi et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Arylamine N-acetyltransferase I
Rodney F. Minchin et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
N-acetyltransferase (Nat) 1 and 2 expression in Nat2 knockout mice
Jennifer A. Loehle et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer
Anna V. Ivshina et al.
CANCER RESEARCH (2006)
Tobacco smoking, NAT2 acetylation genotype and breast cancer risk
Jolanta Lissowska et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
NMR-based model reveals the structural determinants of mammalian arylamine N-acetyltransferase substrate specificity
Naixia Zhang et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Identification and characterization of functional rat arylamine N-acetyltransferase 3:: Comparisons with rat arylamine N-acetyltransferases 1 and 2
Jason M. Walraven et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice
K. S. Sugamori et al.
DRUG METABOLISM AND DISPOSITION (2006)
Risk of limb deficiency defects associated with NAT1, NAT2, GSTT1, GSTM1, and NOS3 genetic variants, maternal smoking, and vitamin supplement intake
Suzan L. Carmichael et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2006)
Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer
Kenneth R. Hess et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Arylamine N-acetyltransferase aggregation and constitutive ubiquitylation
Fen Liu et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Loss of function polymorphisms in NAT1 protect against spina bifida
Liselotte E. Jensen et al.
HUMAN GENETICS (2006)
Functional properties of an alternative, tissue-specific promoter for human arylamine N-acetyltransferase 1
David F. Barker et al.
PHARMACOGENETICS AND GENOMICS (2006)
Hsp70 chaperones accelerate protein translocation and the unfolding of stable protein aggregates by entropic pulling
P De los Rios et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Is the association between cigarette smoking and breast cancer modified by genotype? A review of epidemiologic studies and meta-analysis
PD Terry et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2006)
Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster
DW Hein et al.
MOLECULAR CARCINOGENESIS (2006)
Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes
E Patin et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2006)
Gene expression profiling in breast cancer: Understanding the molecular basis of histologic grade to improve prognosis
C Sotiriou et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)
Characterization of the putative operon containing arylamine N-acetyltransferase (nat) in Mycobacterium bovis BCG
MC Anderton et al.
MOLECULAR MICROBIOLOGY (2006)
Structure and mechanism of arylamine N-acetyltransferases
I. M. Westwood et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2006)
Mutational and expression analysis of tbnat and its response to isoniazid
C Sholto-Douglas-Vernon et al.
JOURNAL OF MEDICAL MICROBIOLOGY (2005)
An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival
LD Miller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines
J Sandy et al.
BIOCHEMICAL JOURNAL (2005)
The NAT1 C1095A polymorphism, maternal multivitamin use and smoking, and the risk of spina bifida
LE Jensen et al.
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2005)
Human thiopurine S-methyltransferase pharmacogenetics:: Variant allozyme misfolding and aggresome formation
LW Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Folding and quality control of the VHL tumor suppressor proceed through distinct chaperone pathways
AJ McClellan et al.
CELL (2005)
Structural analysis of the genes for human arylamine N-acetyltransferases and characterisation of alternative transcripts
S Boukouvala et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2005)
Arylamine N-acetyltransferase 2 expression in the developing heart
L Wakefield et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2005)
Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5′-UTR splice variants with altered translational activities
NJ Butcher et al.
BIOCHEMICAL JOURNAL (2005)
Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation
EJ Bennett et al.
MOLECULAR CELL (2005)
Only low levels of exogenous N-acetyltransferase can be achieved in transgenic mice
W Cao et al.
PHARMACOGENOMICS JOURNAL (2005)
Eukaryotic arylamine N-acetyltransferase investigation of substrate specificity by high-throughput screening
A Kawamura et al.
BIOCHEMICAL PHARMACOLOGY (2005)
Arylamine N-acetyltransferases: What we learn from genes and genomes
S Boukouvala et al.
DRUG METABOLISM REVIEWS (2005)
Maternal smoking and the risk of orofacial clefts - Susceptibility with NAT1 and NAT2 polymorphisms
EJ Lammer et al.
EPIDEMIOLOGY (2004)
Active solubilization and refolding of stable protein aggregates by cooperative unfolding action of individual Hsp70 chaperones
A Ben-Zvi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Identification of the major promoter and non-coding exons of the human arylamine N-acetyltransferase 1 gene (NAT1)
A Husain et al.
PHARMACOGENETICS (2004)
The T341C (lle114Thr) polymorphism of N-acetyltransferase 2 yields slow acetylator phenotype by enhanced protein degradation
Y Zang et al.
PHARMACOGENETICS (2004)
Active-site alkylation destabilizes human O-6-alkylguanine DNA alkyltransferase
JJ Rasimas et al.
PROTEIN SCIENCE (2004)
Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for Orofacial clefts
EJ Lammer et al.
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2004)
Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine -: A mechanism for the slow acetylator phenotype and substrate-dependent down-regulation
NJ Butcher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
ONCOMINE: A cancer microarray database and integrated data-mining platform
DR Rhodes et al.
NEOPLASIA (2004)
Arylamine N-acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target
S Bhakta et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Relationship between intratumoral expression of genes coding for xenobiotic-metabolizing enzymes and benefit from adjuvant tamoxifen in estrogen receptor alpha-positive postmenopausal breast carcinoma
I Bieche et al.
BREAST CANCER RESEARCH (2004)
Identification of a minimal promoter sequence for the human N-acetyltransferase Type I gene that binds AP-1 (activator protein 1) and YY-1 (Yin and Yang 1)
NJ Butcher et al.
BIOCHEMICAL JOURNAL (2003)
Structure and transcriptional regulation of the Nat2 gene encoding for the drug-metabolizing enzyme arylamine N-acetyltransferase type 2 in mice
S Boukouvala et al.
BIOCHEMICAL JOURNAL (2003)
Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice
KS Sugamori et al.
MOLECULAR PHARMACOLOGY (2003)
An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases
EW Brooke et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2003)
How the ubiquitin-proteasome system controls transcription
M Muratani et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Generation and analysis of mice with a targeted disruption of the arylamine N-acetyltransferase type 2 gene
VA Cornish et al.
PHARMACOGENOMICS JOURNAL (2003)
Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity
H Sakahira et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis
DW Hein
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2002)
Cytoplasmic dynein/dynactin mediates the assembly of aggresomes
JA Johnston et al.
CELL MOTILITY AND THE CYTOSKELETON (2002)
Identification and functional characterization of novel polymorphisms associated with the genes for arylamine N-acetyltransferases in mice
S Boukouvala et al.
PHARMACOGENETICS (2002)
Gene expression - Emerging roles of ubiquitin in transcription regulation
RC Conaway et al.
SCIENCE (2002)
The structure of arylamine N-acetyltransferase from mycobacterium smegmatis -: An enzyme which inactivates the anti-tubercular drug, Isoniazid
J Sandy et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Degradation of the alkylated form of the DNA repair protein, O6-alkylguanine-DNA alkyltransferase
M Xu-Welliver et al.
CARCINOGENESIS (2002)
The COOH terminus of arylamine N-acetyltransferase from Salmonella typhimurium controls enzymic activity
A Mushtaq et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Gene expression profiling predicts clinical outcome of breast cancer
LJ van't Veer et al.
NATURE (2002)
The pharmacogenetics of NAT: structural aspects
F Pompeo et al.
PHARMACOGENOMICS (2002)
Arylamine N-acetyltransferase of Mycobacterium tuberculosis is a polymorphic enzyme and a site of isoniazid metabolism
AM Upton et al.
MOLECULAR MICROBIOLOGY (2001)
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
T Sorlie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
N-acetyltransferases, sulfotransferases and heterocyclic amine activation in the breast
JA Williams et al.
PHARMACOGENETICS (2001)
Identification and functional characterization of arylamine N-acetyltransferases in eubacteria:: Evidence for highly selective acetylation of 5-aminosalicylic acid
C Deloménie et al.
JOURNAL OF BACTERIOLOGY (2001)
Eubacterial arylamine N-acetyltransferases -: identification and comparison of 18 members of the protein family with conserved active site cysteine, histidine and aspartate residues
M Payton et al.
MICROBIOLOGY-SGM (2001)
Sumo, ubiquitin's mysterious cousin
S Müller et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Placental arylamine N-acetyltransferase type 1:: potential contributory source of urinary folate catabolite p-acetamidobenzoylglutamate during pregnancy
A Upton et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2000)
Aggresomes, inclusion bodies and protein aggregation
RR Kopito
TRENDS IN CELL BIOLOGY (2000)
The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases
PK Jackson et al.
TRENDS IN CELL BIOLOGY (2000)
Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
U Schubert et al.
NATURE (2000)
Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos
VA Smelt et al.
HUMAN MOLECULAR GENETICS (2000)
Repair of O6-alkylguanine by alkyltransferases
AE Pegg
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2000)
Chromosome mapping of the genes for murine arylamine N-acetyltransferases (NATs), enzymes involved in the metabolism of carcinogens: identification of a novel upstream noncoding exon for murine Nat2
G Fakis et al.
CYTOGENETICS AND CELL GENETICS (2000)