4.1 Review

Scaling Pharmacodynamics from In Vitro and Preclinical Animal Studies to Humans

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Development of translational pharmacokinetic-pharmacodynamic models

D. E. Mager et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2008)

Article Pharmacology & Pharmacy

Target-mediated pharmacokinetic and pharmacodynamic model of recombinant human erythropoietin (rHuEPO)

Sukyung Woo et al.

JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2007)

Article Chemistry, Multidisciplinary

Allometric scaling of pharmacodynamic responses:: Application to 5-Ht1A receptor mediated responses from rat to man

Klaas P. Zuideveld et al.

PHARMACEUTICAL RESEARCH (2007)

Article Pharmacology & Pharmacy

Interspecies comparisons of pharmacokinetics and pharmacodynamics of recombinant human erythropoietin

Sukyung Woo et al.

DRUG METABOLISM AND DISPOSITION (2007)

Review Biochemistry & Molecular Biology

Whole-body physiologically based pharmacokinetic models

Ivan Nestorov

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2007)

Article Pharmacology & Pharmacy

Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after intravenous and subcutaneous administration in rats

Sukyung Woo et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)

Review Pharmacology & Pharmacy

Quantitative structure-pharmacokinetic/pharmacodynamic relationships

Donald E. Mager

ADVANCED DRUG DELIVERY REVIEWS (2006)

Article Radiology, Nuclear Medicine & Medical Imaging

Population pharmacokinetic analysis for simultaneous determination of Bmax and KD in vivo by positron emission tomography

LC Liefaard et al.

MOLECULAR IMAGING AND BIOLOGY (2005)

Article Chemistry, Medicinal

An evaluation of the utility of physiologically based models of pharmacokinetics in early drug discovery

N Parrott et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2005)

Article Chemistry, Multidisciplinary

Quasi-equilibrium pharmacokinetic model for drugs exhibiting target-mediated drug disposition

DE Mager et al.

PHARMACEUTICAL RESEARCH (2005)

Article Chemistry, Multidisciplinary

Disease system analysis: Basic disease progression models in degenerative disease

TM Post et al.

PHARMACEUTICAL RESEARCH (2005)

Article Pharmacology & Pharmacy

Modeling and allometric scaling of s(+)-ketoprofen pharmacokinetics and pharmacodynamics: a retrospective analysis

EI Lepist et al.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS (2004)

Article Chemistry, Medicinal

Interspecies scaling of protein drugs: Prediction of clearance from animals to humans

I Mahmood

JOURNAL OF PHARMACEUTICAL SCIENCES (2004)

Review Chemistry, Medicinal

Antibody pharmacokinetics and pharmacodynamics

ED Lobo et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2004)

Review Pharmacology & Pharmacy

Diversity of mechanism-based pharmacodynamic models

DE Mager et al.

DRUG METABOLISM AND DISPOSITION (2003)

Article Pharmacology & Pharmacy

Dose equivalency evaluation of major corticosteroids: Pharmacokinetics and cell trafficking and cortisol dynamics

DE Mager et al.

JOURNAL OF CLINICAL PHARMACOLOGY (2003)

Article Pharmacology & Pharmacy

General pharmacokinetic model for drugs exhibiting target-mediated drug disposition

DE Mager et al.

JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2001)