4.7 Review

Silica-based nanoparticles for biomedical applications

Journal

DRUG DISCOVERY TODAY
Volume 17, Issue 19-20, Pages 1147-1154

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2012.06.014

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In this short review we highlight novel uses of silica-based nanoparticles (NPs) in the biomedical sector. Silica NPs are widely used in nanotechnology because they are easy to prepare and inexpensive to produce. Their specific surface characteristics, porosity and capacity for fimctionalization make them good tools for biomolecule detection and separation, providing solid media for drug delivery systems and acting as contrast agent protectors. In addition, they are used as safety and biocompatible pharmaceutical additives. Here, we focus on novel techniques based on silica NPs for the most important biomedical applications.

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