Journal
DRUG DISCOVERY TODAY
Volume 17, Issue 19-20, Pages 1111-1120Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2012.06.002
Keywords
-
Categories
Funding
- National Institutes of Health [GM58187, AI23007]
Ask authors/readers for more resources
Seasonal and pandemic influenza have caused high morbidity and mortality worldwide. Recent emergence of influenza A H5N1 and H1N1 strains has heightened concern, especially as a result of their drug resistance. The life cycle of influenza viruses has been well studied and nearly all the viral proteins are becoming potential therapeutic targets. In this review, we present an overview of recent progress in structure-based anti-influenza drug design, paying close attention to the increasing role of computation and strategies for overcoming drug resistance.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available