Journal
DRUG DISCOVERY TODAY
Volume 16, Issue 23-24, Pages 1037-1043Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2011.09.007
Keywords
-
Categories
Ask authors/readers for more resources
Novel therapeutics in areas with a high unmet medical need are based on innovative drug targets. Although 'biologicals' have enlarged the space of druggable molecules, the number of appropriate drug targets is still limited. Discovering and assessing the potential therapeutic benefit of a drug target is based not only on experimental, mechanistic and pharmacological studies but also on a theoretical molecular druggability assessment, an early evaluation of potential side effects and considerations regarding opportunities for commercialization. This article defines key properties of a good drug target from the perspective of a pharmaceutical company.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available