Journal
DRUG DISCOVERY TODAY
Volume 13, Issue 21-22, Pages 932-943Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2008.07.010
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- Faculty of Pharmacy, Jamia Hamdard, New Delhi
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Periodontal disease is a localised inflammatory response caused by the infection of a periodontal pocket arising from the accumulation of subgingival plaque. Periodontal disease has been considered as a possible risk factor for other systemic diseases such as cardiovascular diseases and pre-term low birth weight infants. Advances in understanding the aetiology, epidemiology and microbiology of periodontal pocket flora have revolutionised the therapeutic strategies for the management of periodontal disease progression. This review summarises the recent developments in the field of intra-pocket drug delivery systems and identifies areas where further research may lead to a clinically effective intra-pocket delivery system.
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