Journal
DRUG DISCOVERY TODAY
Volume 13, Issue 9-10, Pages 417-423Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2008.03.005
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The broad coordinated implementation of common platform technologies, such as LC/MS, can be a key factor in attaining increased throughput, sensitivity and data quality for pharmaceutical discovery. These platform technologies are the key tools that Medicinal Analytical Chemists rely upon to address the ever-changing needs of a drug discovery team. Despite the recent advances in key areas of sensitivity and speed for LC/MS, additional progress to address these never-ending analytical problems can be anticipated. This review will highlight current status and future advances for the applications of LC/MS and related techniques to high-throughput drug discovery.
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