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Alginate drug delivery systems: application in context of pharmaceutical and biomedical research

Journal

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
Volume 40, Issue 12, Pages 1576-1584

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.3109/03639045.2014.917657

Keywords

Beads; floating systems; membranes; microspheres; nanoparticles; sodium alginate

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Alginates are natural polymers widely used in the food industry because of their biocompatible, biodegradable character, nontoxicity and easy availability. The bioadhesive character of alginates makes them useful in the pharmaceutical industry as well. The application areas of sodium alginate-based drug delivery systems are many and these systems can be formulated as gels, matrices, membranes, nanospheres, microspheres, etc. Worldwide researchers are exploring possible applications of alginates as coating material, preparation of controlled-release drug delivery systems such as microspheres, beads, pellets, gels, fibers, membranes, etc. In the present review, such applications of alginates are discussed.

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