4.7 Article

Visualization of Connexin 43-positive cells of glioma and the periglioma zone by means of intravenously injected monoclonal antibodies

Journal

DRUG DELIVERY
Volume 18, Issue 5, Pages 331-337

Publisher

INFORMA HEALTHCARE
DOI: 10.3109/10717544.2010.549527

Keywords

Gap-junction; monoclonal antibodies; glioma; targeted delivery

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The selectivity of monoclonal antibodies against the E2 extracellular fragment of connexin 43 (Cx43) for a glioma focus was studied in in vivo experiments on animals with intracranial C6 glioma. Antibodies labeled with two alternative labels, the radioisotope

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