Journal
DRUG AND CHEMICAL TOXICOLOGY
Volume 33, Issue 2, Pages 173-182Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/01480540903311068
Keywords
Antioxidant; atherosclerosis; chlorophytum borivilianum; LDL oxidation; lipid peroxidation; phenolic compounds
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Chlorophytum borivilianum is a very popular herb in traditional Indian medicine and used as a potent Rasayana drug in Ayurveda as a rejuvenator. Currently, a large body of evidence supports the key role of free radicals in diverse pathological conditions such as aging and atherosclerosis. The present investigation essentially focuses on the comprehensive account of in vitro antioxidant activity exerted by C.borivilianum root extracts (i.e., aqueous and ethanolic), to clarify the pharmacological antagonism of chemicals/metals-mediated oxidation. Graded-dose (25 to 1000 mu g/ml) of aqueous extract exhibited higher antioxidant potency as evidenced by powerful nitric oxide, superoxide, hydroxyl, DPPH and ABTS
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