Journal
DRUG AND ALCOHOL DEPENDENCE
Volume 112, Issue 3, Pages 178-193Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.drugalcdep.2010.06.014
Keywords
HIV/AIDS; Alcohol use disorders; Systematic review; Adherence; Health care utilization
Categories
Funding
- National Institute on Drug Abuse [K23 DA019381, K24 DA017072]
- National Institute on Alcohol Abuse and Alcoholism [R01 AA018944]
- National Institute of Allergy and Infectious Diseases [T32-AI007517-10]
Ask authors/readers for more resources
Background Alcohol use disorders (AUDs) are highly prevalent and associated with non-adherence to antiretroviral therapy decreased health care utilization and poor HIV treatment outcomes among HIV-infected individuals Objectives To systematically review studies assessing the impact of AUDs on (1) medication adherence (2) health care utilization and (3) biological treatment outcomes among people living with HIV/AIDS (PLWHA) Data sources Six electronic databases and Google Scholar were queried for articles published in English French and Spanish from 1988 to 2010 Selected references from primary articles were also examined Review methods Selection criteria included (1) AUD and adherence (N = 20) (2) AUD and health services utilization (N = 11) or (3) AUD with CD4 count or HIV-1 RNA treatment outcomes (N = 10) Reviews animal studies non-peer reviewed documents and ongoing studies with unpublished data were excluded Studies that did not differentiate HIV+ from HIV status and those that did not distinguish between drug and alcohol use were also excluded Data were extracted appraised and summarized Data synthesis and conclusions Our findings consistently support an association between AUDs and decreased adherence to antiretroviral therapy and poor HIV treatment outcomes among HIV-Infected individuals Their effect on health care utilization however was variable (C) 2010 Elsevier Ireland Ltd All rights reserved
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available