4.2 Article

CANCER MORTALITY FOR A SINGLE RACE IN LOW VERSUS HIGH ELEVATION COUNTIES IN THE US

Journal

DOSE-RESPONSE
Volume 9, Issue 3, Pages 348-355

Publisher

INT DOSE-RESPONSE SOC
DOI: 10.2203/dose-response.10-014.Hart

Keywords

Background radiation; cancer death rates; altitude; medical geography; Caucasian race

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A previous study compared cancer mortality in the six lowest versus six highest elevations in the U. S. for all races. This study looks at a single race since death rates tend to vary by race. In this ecological study, cancer mortality rates were compared between low and high states for a race that had sufficient number of counties reporting mortality data, that is, the white race. The average cancer mortality rate for low elevation counties was 73.47 + 18.35 compared to 53.90 + 13.76 for high elevation counties, a difference that was statistically significant (p < 0.0001), with a very large effect size (of 1.2). Higher elevation counties showed less cancer mortality rates for a single race compared to lower elevation counties, suggesting the presence of radiation hormesis. Further rigorous research is indicated to verify or refute these findings.

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