Journal
DNA REPAIR
Volume 17, Issue -, Pages 39-51Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.dnarep.2014.02.008
Keywords
Double strand break repair; Nonhomologous end joining; DNA damage
Categories
Funding
- NIH [CA84442, CA097096]
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Double strand breaks pose unique problems for DNA repair, especially when broken ends possess complex structures that interfere with standard DNA transactions. Nonhomologous end joining can use multiple strategies to solve these problems. It further uses sophisticated means to ensure the strategy chosen provides the ideal balance of flexibility and accuracy. (C) 2014 Elsevier B.V. All rights reserved.
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