Journal
DNA REPAIR
Volume 9, Issue 3, Pages 345-353Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.dnarep.2009.12.008
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Funding
- Association of International Cancer Research (AICR)
- Cancer Research UK
- Cancer Research UK [11567] Funding Source: researchfish
- Worldwide Cancer Research [09-0730] Funding Source: researchfish
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The RecQ family of helicases are traditionally viewed as recombination factors, important for maintaining genome stability. RECQL5 is unique among these proteins in being associated with RNA polymerase II, the enzyme responsible for transcribing all protein-encoding genes in eukaryotes. Here, we describe the possible implications of recent studies and discuss models for RECQL5 function. (C) 2010 Elsevier B.V. All rights reserved.
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