Journal
DISEASES OF THE COLON & RECTUM
Volume 53, Issue 2, Pages 219-223Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1007/DCR.0b013e3181b715b5
Keywords
Cylindrical abdominoperineal resection; Pelvic reconstruction; Human acellular dermal matrix; Complication
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Funding
- New Century Educational Talents Plan of Chinese Education Ministry, China [NCET-05-0200]
- National Natural Science Fund Projects, China [30772123]
- Program for Outstanding Medical Academic Leader, Beijing [2009-1-03]
- Youth Foundation of Beijing Chaoyang Hospital
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PURPOSE: Patients who undergo cylindrical abdominoperineal resection can have significant complications, especially those who require pelvic reconstruction using myocutaneous flaps. Reconstruction using a biomaterial may be a novel alternative. The purpose of this study is to report the initial results of pelvic reconstruction using human acellular dermal matrix after cylindrical abdominoperineal resection. METHODS: Between January 2008 and February 2009, pelvic floor reconstruction was performed in 12 consecutive patients who underwent cylindrical abdominoperineal resection for advanced ultralow rectal cancer. RESULTS: Two weeks after the operation, primary complete healing of the perineal wound was seen in 11 patients. At a median follow-up of 8 months, there was no perineal wound breakdown, bulge, or herniation. One patient had an asymptomatic seroma, one patient had a perineal wound infection, and 4 patients had perineal pain that resolved. CONCLUSIONS: Human acellular dermal matrix provided a safe alternative for the reconstruction of large pelvic defect in the patients after cylindrical abdominoperineal resection.
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