Journal
DISEASE MARKERS
Volume 24, Issue 4-5, Pages 251-255Publisher
HINDAWI LTD
DOI: 10.1155/2008/747343
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Funding
- NCI NIH HHS [R01 CA106614A, R01 CA4285718A] Funding Source: Medline
- NIDDK NIH HHS [R01 DK58637, R01 DK56111] Funding Source: Medline
- NATIONAL CANCER INSTITUTE [R01CA042857] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R01DK056111] Funding Source: NIH RePORTER
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Transforming growth factor beta (TGF-beta) signaling has diverse and complex roles in various biological phenomena such as cell growth, differentiation, embryogenesis and morphogenesis. ES cells provide an essential model for understanding the role of TGF-beta signaling in lineage specification and differentiation. Recent studies have suggested significant role of TGF-beta in stem/progenitor cell biology. Here in this review, we focus on the role of the TGF-beta superfamily in neuronal development.
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