4.5 Article

PREVALENCE AND CLINICOPATHOLOGICAL FEATURES OF NONPOLYPOID COLORECTAL NEOPLASMS: SHOULD WE PAY MORE ATTENTION TO IDENTIFYING FLAT AND DEPRESSED LESIONS?

Journal

DIGESTIVE ENDOSCOPY
Volume 22, Issue -, Pages S57-S62

Publisher

WILEY-BLACKWELL
DOI: 10.1111/j.1443-1661.2010.00967.x

Keywords

Japan Polyp Study; nonpolypoid colorectal neoplasm; screening colonoscopy

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Flat and depressed (nonpolypoid) colorectal lesions have been described for over two decades by Japanese investigators. These neoplastic lesions are typically smaller than polypoid ones and can be more difficult to identify during screening colonoscopy. In particular, depressed type colorectal lesions are usually small in size, with a number of studies showing them to be at greater risk for developing high-grade dysplasia or submucosal invasive cancer. It has also been suggested that they may follow a different carcinogenic pathway to flat elevated or protruding adenomas. This paper summarizes recent data of nonpolypoid colorectal neoplasms from Western and Asian countries.

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