Journal
DIGESTIVE AND LIVER DISEASE
Volume 43, Issue -, Pages S2-S7Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S1590-8658(10)60685-8
Keywords
Hepatitis B; Strategies of immunization; Vaccination
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Funding
- University of Antwerp
- Sanofi Pasteur MSD
- GlaxoSmithKline
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Viral hepatitis B is a leading cause of acute and chronic liver disease worldwide, including cirrhosis and hepatocellular carcinoma. Vaccination is the most effective measure for controlling and preventing hepatitis B and its severe long-term sequelae. According to the World Health Organization (WHO), by the end of 2008 177 countries had introduced hepatitis B vaccination into their national routine neonatal, infant and/or adolescent immunisation programmes, and Italy was one of the first countries to implement a universal strategy of hepatitis B vaccination. The implementation of such vaccination programmes has globally resulted in a marked decrease in disease burden, in the carrier rate and in hepatitis B-related morbidity and mortality. Despite this success, work remains to be done to fully achieve the WHO goal of control of hepatitis B and HBV-related diseases on a global scale. (C) 2010 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
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