Journal
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
Volume 79, Issue 2, Pages 178-182Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2014.02.012
Keywords
HPV detection; Isothermal helicase-dependent amplification; Cost-effective method; Cervical cancer
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Persistent infection with human papillomavirus (HPV) induces cervical cancer. Here, we describe a sensitive, specific, and rapid assay for high-risk HPV16 and 18 detection by isothermal helicase-dependent amplification. This method can be used as cost-effective diagnostic method for low-income countries, where highest incidences worldwide of cervical cancer are registered. (C) 2014 Elsevier Inc. All rights reserved.
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