Journal
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
Volume 73, Issue 2, Pages 204-206Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2012.02.007
Keywords
Carbapenemase; Sewage; Resistance; Plasmid
Categories
Funding
- National Natural Science Foundation of China [30900052]
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Fifteen isolates with reduced susceptibility to meropenem were obtained from hospital sewage. They contained bla(KPC-2) and belonged to multiple clones of Citrobacter freundii or Enterobacter cloacae. bla(KPC-2) was commonly carried by self-transmissible plasmids with different EcoRI-restricted patterns. Tn2 was identified upstream of bla(KPC-2), while ISKpn6 lay downstream. Hospital sewage could be an important reservoir of bla(KPC-2) and warrants more studies. (C) 2012 Elsevier Inc. All rights reserved.
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