4.3 Article

First molecular method for discriminating between Candida africana, Candida albicans, and Candida dubliniensis by using hwp1 gene

Journal

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
Volume 62, Issue 2, Pages 230-233

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2008.05.014

Keywords

Candida africana; Candida albicans; Candida dublinensis; hwp1 gene; PCR-based assay

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The authors report here a polymerase chain reaction-based assay using a single primer pair (CR-f/CR-r), allowing discrimination between Canclicla africana and Candida albicans by using the hwp1 gene. The method also identifies Candida dubliniensis because it produces 3 different DNA fragments: approximately 700 bp for C. africana, 941 bp for C. albicans, and 569 for C. dubliniensis. (C) 2008 Elsevier Inc. All rights reserved.

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