Journal
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
Volume 62, Issue 2, Pages 162-166Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2007.10.012
Keywords
influenza virus; rapid test; Binax NOW; direct fluorescent assay; sensitivity; specificity
Categories
Funding
- NCPDCID CDC HHS [1 U01 CI000192-01] Funding Source: Medline
Ask authors/readers for more resources
The Binax NOW Flu A and Flu B (Binax NOW), direct fluorescent assay (DFA), and viral culture were evaluated and compared with a composite of viral Culture or reverse transcription polymerase chain reaction (RT-PCR). Participants with medically attended acute respiratory illness were identified through active surveillance during the 2006 to 2007 season, and consenting individuals (n = 932) were tested for influenza by Culture and RT-PCR. Physicians ordered a rapid antigen test (Binax NOW [n = 73] or DFA [n = 70]) according to their clinical judgment. The Binax NOW detected 11 of 18 influenza infections (sensitivity, 61%; 95% confidence interval [CI], 36-83%)), whereas DFA detected 17 of 21 influenza infections (sensitivity 81%, 95% Cl, 58-95%). Compared with culture/RT-PCR, specificity of both Binax NOW and DFA was 100%. During the 2006 to 2007 Influenza season, DFA and Binax NOW demonstrated high specificity but failed to identify a substantial proportion Of Influenza infections. (C) 2008 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available