4.2 Review

The role of dynamic contrast-enhanced MRI in cancer diagnosis and treatment

Journal

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY
Volume 16, Issue 3, Pages 186-192

Publisher

AVES
DOI: 10.4261/1305-3825.DIR.2537-08.1

Keywords

pathologic angiogenesis; angiogenic inhibitors; magnetic resonance imaging

Funding

  1. Intramural NIH HHS [Z01 BC010714-03] Funding Source: Medline
  2. NATIONAL CANCER INSTITUTE [ZIABC010714, ZIABC010655] Funding Source: NIH RePORTER

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Angiogenesis is a key step in the pathophysiology of tumor growth and metastatic spread. Recently, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has emerged as a method for assessing angiogenesis both during the initial diagnosis and for follow up of anti-angiogenic therapies. In this review, we discuss the technical aspects of implementing DCE-MRI in clinical practice with emphasis on acquisition methods and analytic techniques.

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