Related references
Note: Only part of the references are listed.Mechanisms for Insulin Resistance: Common Threads and Missing Links
Varman T. Samuel et al.
CELL (2012)
FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling
Rudolf Zechner et al.
CELL METABOLISM (2012)
Inhibiting Adipose Tissue Lipogenesis Reprograms Thermogenesis and PPARγ Activation to Decrease Diet-Induced Obesity
Irian J. Lodhi et al.
CELL METABOLISM (2012)
Regulation of glucose/lipid metabolism and insulin sensitivity by interleukin-4
Y-H Chang et al.
INTERNATIONAL JOURNAL OF OBESITY (2012)
Phenotypic Discrepancies in Acetyl-CoA Carboxylase 2-deficient Mice
Kyle L. Hoehn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Liver-specific p70 S6 Kinase Depletion Protects against Hepatic Steatosis and Systemic Insulin Resistance
Eun Ju Bae et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
Marica Bordicchia et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver
Renaud Dentin et al.
JOURNAL OF HEPATOLOGY (2012)
Postlipolytic insulin-dependent remodeling of micro lipid droplets in adipocytes
Nicholas Ariotti et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism
Mark A. Herman et al.
NATURE (2012)
MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity
Christine M. Kusminski et al.
NATURE MEDICINE (2012)
The cellular and signaling networks linking the immune system and metabolism in disease
Olivia Osborn et al.
NATURE MEDICINE (2012)
Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice
Robert W. O'Rourke et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2012)
Preventing Phosphorylation of Sterol Regulatory Element-Binding Protein 1a by MAP-Kinases Protects Mice from Fatty Liver and Visceral Obesity
Jorg Kotzka et al.
PLOS ONE (2012)
Interleukin-7 Regulates Adipose Tissue Mass and Insulin Sensitivity in High-Fat Diet-Fed Mice through Lymphocyte-Dependent and Independent Mechanisms
Stephanie Lucas et al.
PLOS ONE (2012)
Distinct mTORC1 pathways for transcription and cleavage of SREBP-1c
William J. Quinn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice
Lan Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling
Jeremie Boucher et al.
NATURE COMMUNICATIONS (2012)
Role of S6K1 in regulation of SREBP1c expression in the liver
Shuying Li et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity
Carmen Hurtado del Pozo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2011)
Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity
Pingping Li et al.
CELL (2011)
mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway
Timothy R. Peterson et al.
CELL (2011)
Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways
Jessica L. Yecies et al.
CELL METABOLISM (2011)
Brain Insulin Controls Adipose Tissue Lipolysis and Lipogenesis
Thomas Scherer et al.
CELL METABOLISM (2011)
Mice with AS160/TBC1D4-Thr649Ala Knockin Mutation Are Glucose Intolerant with Reduced Insulin Sensitivity and Altered GLUT4 Trafficking
Shuai Chen et al.
CELL METABOLISM (2011)
Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice
Xavier Prieur et al.
DIABETES (2011)
Fatty Acids, Obesity, and Insulin Resistance: Time for a Reevaluation
Fredrik Karpe et al.
DIABETES (2011)
Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis
Fiona C. McGillicuddy et al.
DIABETES (2011)
Deficiency of haematopoietic-cell-derived IL-10 does not exacerbate high-fat-diet-induced inflammation or insulin resistance in mice
G. M. Kowalski et al.
DIABETOLOGIA (2011)
IL-6 induces lipolysis and mitochondrial dysfunction, but does not affect insulin-mediated glucose transport in 3T3-L1 adipocytes
Chenbo Ji et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2011)
Relative Contribution of Adipose Triglyceride Lipase and Hormone-sensitive Lipase to Tumor Necrosis Factor-α (TNF-α)-induced Lipolysis in Adipocytes
Xingyuan Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Monoglyceride Lipase Deficiency in Mice Impairs Lipolysis and Attenuates Diet-induced Insulin Resistance
Ulrike Taschler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
TNF-alpha Antagonism with Etanercept Decreases Glucose and Increases the Proportion of High Molecular Weight Adiponectin in Obese Subjects with Features of the Metabolic Syndrome
Takara L. Stanley et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice
William L. Holland et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Elevated Proinflammatory Cytokine Production by a Skewed T Cell Compartment Requires Monocytes and Promotes Inflammation in Type 2 Diabetes
Madhumita Jagannathan-Bogdan et al.
JOURNAL OF IMMUNOLOGY (2011)
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
Daniel A. Winer et al.
NATURE MEDICINE (2011)
Visceral Adipose Inflammation in Obesity Is Associated with Critical Alterations in Tregulatory Cell Numbers
Jeffrey Deiuliis et al.
PLOS ONE (2011)
Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis
Davina Wu et al.
SCIENCE (2011)
The Effects of Salsalate on Glycemic Control in Patients With Type 2 Diabetes A Randomized Trial
Allison B. Goldfine et al.
ANNALS OF INTERNAL MEDICINE (2010)
Natural Killer T Cells Are Involved in Adipose Tissues Inflammation and Glucose Intolerance in Diet-Induced Obese Mice
Kazue Ohmura et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2010)
Lipid oversupply, selective insulin resistance, and lipotoxicity: Molecular mechanisms
Jose Antonio Chavez et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)
The Impact of Macrophage Insulin Resistance on Advanced Atherosclerotic Plaque Progression
Ira Tabas et al.
CIRCULATION RESEARCH (2010)
Interleukin-33 Induces Protective Effects in Adipose Tissue Inflammation During Obesity in Mice
Ashley M. Miller et al.
CIRCULATION RESEARCH (2010)
Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis, Stimulates Lipogenesis, and Promotes Fat Storage
Partha Chakrabarti et al.
DIABETES (2010)
Suppressive Effect of Insulin Infusion on Chemokines and Chemokine Receptors
Husam Ghanim et al.
DIABETES CARE (2010)
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance
V. B. Matthews et al.
DIABETOLOGIA (2010)
IGF-I Activation of the AKT Pathway Is Impaired in Visceral But Not Subcutaneous Preadipocytes from Obese Subjects
Kelly Cleveland-Donovan et al.
ENDOCRINOLOGY (2010)
The N-terminal Region of Comparative Gene Identification-58 (CGI-58) Is Important for Lipid Droplet Binding and Activation of Adipose Triglyceride Lipase
Astrid Gruber et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
Aliki Kosteli et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
IL-10 inhibits transcription elongation of the human TNF gene in primary macrophages
Tim Smallie et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
5-Lipoxygenase Activating Protein Signals Adipose Tissue Inflammation and Lipid Dysfunction in Experimental Obesity
Raquel Horrillo et al.
JOURNAL OF IMMUNOLOGY (2010)
IL-17 Regulates Adipogenesis, Glucose Homeostasis, and Obesity
Luis A. Zuniga et al.
JOURNAL OF IMMUNOLOGY (2010)
Lipid-induced insulin resistance: unravelling the mechanism
Varman T. Samuel et al.
LANCET (2010)
The Gene Expression of the Main Lipogenic Enzymes is Downregulated in Visceral Adipose Tissue of Obese Subjects
Francisco J. Ortega et al.
OBESITY (2010)
IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity
Roberto R. Ricardo-Gonzalez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Myeloid Cell-Restricted Insulin Receptor Deficiency Protects Against Obesity-Induced Inflammation and Systemic Insulin Resistance
Jan Mauer et al.
PLOS GENETICS (2010)
Effect of hyperinsulinemia and very-low-calorie diet on interstitial cytokine levels in subcutaneous adipose tissue of obese women
Michaela Siklova-Vitkova et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation
Andrew J. Hoy et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Protein kinase B activity is required for the effects of insulin on lipid metabolism in adipocytes
Christine Berggreen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
The PPARγ agonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake
William T. Festuccia et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)
Interplay Between Human Adipocytes and T Lymphocytes in Obesity CCL20 as an Adipochemokine and T Lymphocytes as Lipogenic Modulators
Carine Duffaut et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)
PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores
Perry E. Bickel et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2009)
Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling
Alicia H. Clementi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2009)
A Role of DNA-PK for the Metabolic Gene Regulation in Response to Insulin
Roger H. F. Wong et al.
CELL (2009)
TNF-alpha, a potent lipid metabolism regulator
Xiuping Chen et al.
CELL BIOCHEMISTRY AND FUNCTION (2009)
CXC Ligand 5 Is an Adipose-Tissue Derived Factor that Links Obesity to Insulin Resistance
Carine Chavey et al.
CELL METABOLISM (2009)
FoxO1 Links Insulin Resistance to Proinflammatory Cytokine IL-1β Production in Macrophages
Dongming Su et al.
DIABETES (2009)
Interleukin-10 Prevents Diet-Induced Insulin Resistance by Attenuating Macrophage and Cytokine Response in Skeletal Muscle
Eun-Gyoung Hong et al.
DIABETES (2009)
Obesity predisposes to Th17 bias
Shawn Winer et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
Interferon γ Attenuates Insulin Signaling, Lipid Storage, and Differentiation in Human Adipocytes via Activation of the JAK/STAT Pathway
Fiona C. McGillicuddy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Functional interaction of hormone-sensitive lipase and perilipin in lipolysis
Wen-Jun Shen et al.
JOURNAL OF LIPID RESEARCH (2009)
Depot-specific effects of the PPARγ agonist rosiglitazone on adipose tissue glucose uptake and metabolism
William T. Festuccia et al.
JOURNAL OF LIPID RESEARCH (2009)
Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1
Christian C. Dibble et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency
Kathy Jaworski et al.
NATURE MEDICINE (2009)
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
Jian Liu et al.
NATURE MEDICINE (2009)
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
Markus Feuerer et al.
NATURE MEDICINE (2009)
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
Satoshi Nishimura et al.
NATURE MEDICINE (2009)
Normalization of obesity-associated insulin resistance through immunotherapy
Shawn Winer et al.
NATURE MEDICINE (2009)
12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes
Swarup K. Chakrabarti et al.
OBESITY (2009)
PPARγ activation in adipocytes is sufficient for systemic insulin sensitization
Shigeki Sugii et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet
Baukje de Ross et al.
PROTEOMICS (2009)
Cross-Talk between PPAR gamma and Insulin Signaling and Modulation of Insulin Sensitivity
Anna Leonardini et al.
PPAR RESEARCH (2009)
Assessment of fat-specific protein 27 in the adipocyte lineage suggests a dual role for FSP27 in adipocyte metabolism and cell death
Ji Young Kim et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Regulation of PPARγ function by TNF-α
Jianping Ye
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism
Haiming Cao et al.
CELL (2008)
Interferon-γ, a Th1 Cytokine, Regulates Fat Inflammation A Role for Adaptive Immunity in Obesity
Viviane Zorzanelli Rocha et al.
CIRCULATION RESEARCH (2008)
Insulin Resistance and Hyperinsulinemia Is hyperinsulinemia the cart or the horse?
Michael H. Shanik et al.
DIABETES CARE (2008)
The antiinflammatory cytokine interleukin-1 receptor antagonist protects from high-fat diet-induced hyperglycemia
Nadine S. Sauter et al.
ENDOCRINOLOGY (2008)
Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA)
Robin E. Duncan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding
Vered Elgazar-Carmon et al.
JOURNAL OF LIPID RESEARCH (2008)
Reassessing triglyceride synthesis in adipose tissue
Colleen Nye et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2008)
Mechanisms of macrophage activation in obesity-induced insulin resistance
Justin I. Odegaard et al.
NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM (2008)
The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis
Dawn L. Brasaemle
JOURNAL OF LIPID RESEARCH (2007)
Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage
Vishwajeet Puri et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Role of adipocyte-derived lipoprotein lipase in adipocyte hypertrophy
Amanda M. Gonzales et al.
NUTRITION & METABOLISM (2007)
Insulin regulation of lipoprotein lipase (LPL) activity and expression in gilthead sea bream (Sparus aurata)
A. Albalat et al.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2007)
Nicotine-induced activation of AMP-activated protein kinase inhibits fatty acid synthase in 3T3L1 Adipocytes - A role for oxidant stress (Publication with Expression of Concern. See vol. 294, pg. 10025, 2019) (Withdrawn Publication. See vol. 295, pg. 667, 2020)
Zhibo An et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Anti-inflammatory effects of insulin
Paresh Dandona et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2007)
T-cell accumulation and regulated on activation, normal T cell expressed and secreted Upregulation in adipose tissue in obesity
Huaizhu Wu et al.
CIRCULATION (2007)
Direct interaction between USF and SREBP-1c mediates synergistic activation of the fatty-acid synthase promoter
Michael J. Griffin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes
Hideaki Miyoshi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins
Carey N. Lumeng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Carey N. Lumeng et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Potential antiinflammatory role of insulin via the preferential polarization of effector T cells toward a T helper 2 phenotype
Alexander Viardot et al.
ENDOCRINOLOGY (2007)
Role of the Toll-like receptor 4/NF-kappa B pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages
Takayoshi Suganami et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Functional studies of Akt isoform specificity in skeletal muscle in vivo; Maintained insulin sensitivity despite reduced insulin receptor substrate-1 expression
Mark E. Cleasby et al.
MOLECULAR ENDOCRINOLOGY (2007)
OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization
Nathan E. Wolins et al.
DIABETES (2006)
IL-1 receptor antagonist in metabolic diseases: Dr Jekyll or Mr Hyde?
Stephane Perrier et al.
FEBS LETTERS (2006)
Regulation of GLUT4 gene expression by SREBP-1c in adipocytes
Seung-Soon IM et al.
BIOCHEMICAL JOURNAL (2006)
Insulin signaling diverges into Akt-dependent and -independent signals to regulate the recruitment/docking and the fusion of GLUT4 vesicles to the plasma membrane
Eva Gonzalez et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
ChREBP•Mlx is the principal mediator of glucose-induced gene expression in the liver
Lin Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity
QW Wu et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ
Cullen M. Taniguchi et al.
CELL METABOLISM (2006)
Adipose triglyceridelipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome
Achim Lass et al.
CELL METABOLISM (2006)
Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis
J Baumgartl et al.
CELL METABOLISM (2006)
Critical nodes in signalling pathways: insights into insulin action
CM Taniguchi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Protein sensors for membrane sterols
JL Goldstein et al.
CELL (2006)
Decreased fat mass in interleukin-1 receptor antagonist-deficient mice - Impact on adipogenesis, food intake, and energy expenditure
E Somm et al.
DIABETES (2005)
In vivo expression of carbohydrate responsive element binding protein in lean and obese rats
D Letexier et al.
DIABETES & METABOLISM (2005)
G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Gαq/11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes
I Usui et al.
MOLECULAR ENDOCRINOLOGY (2005)
A paracrine loop between adipocytes and macrophages aggravates inflammatory changes -: Role of free fatty acids and tumor necrosis factor α
T Suganami et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein
L Eguez et al.
CELL METABOLISM (2005)
Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes
M Daval et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Atypical protein kinase C in insulin action and insulin resistance
RV Farese et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2005)
Inhibition of fatty acid synthase prevents preadipocyte differentiation
B Schmid et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
DS Cai et al.
NATURE MEDICINE (2005)
Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver
R Dentin et al.
BIOCHIMIE (2005)
Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and Adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans
JN Fain et al.
ENDOCRINOLOGY (2004)
Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-γ
KT Dalen et al.
DIABETES (2004)
Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes
AK Stoeckman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Functional and pharmacological characterization of the natriuretic peptide-dependent lipolytic pathway in human fat cells
C Moro et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Rapid transformation of white adipocytes into fat-oxidizing machines
L Orci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Impact of obesity on plasma natriuretic peptide levels
TJ Wang et al.
CIRCULATION (2004)
Rosiglitazone, an agonist of peroxisome-proliferator-activated receptor γ (PPARγ), decreases inhibitory serine phosphorylation of IRS1 in vitro and in vivo
GQ Jiang et al.
BIOCHEMICAL JOURNAL (2004)
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
SH Um et al.
NATURE (2004)
Modulation of carbohydrate response element-binding protein gene expression in 3T3-L1 adipocytes and rat adipose tissue
ZB He et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
Regulation of insulin action by ceramide - Dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B
S Stratford et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase
R Zimmermann et al.
SCIENCE (2004)
Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity
GB Di Gregorio et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor κB
S Sinha et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis
K Iizuka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Involvement of a cGMP-dependent pathway in the natriuretic peptide-mediated hormone-sensitive lipase phosphorylation in human adipocytes
C Sengenès et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone
C Lagathu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Tumor necrosis factor-α inhibits insulin's stimulating effect on glucose uptake and endothelium-dependent vasodilation in humans
C Rask-Madsen et al.
CIRCULATION (2003)
Adipocyte protein S3-12 coats nascent lipid droplets
NE Wolins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity
M Matsumoto et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Structural and functional organization of the animal fatty acid synthase
S Smith et al.
PROGRESS IN LIPID RESEARCH (2003)
Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing
ZY Jiang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Liver-specific mRNA for Insig-2 down-regulated by insulin: Implications for fatty acid synthesis
D Yabe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Cytokines suppress adipogenesis and PPAR-function through the TAK1/TAB1/NIK cascade
M Suzawa et al.
NATURE CELL BIOLOGY (2003)
Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility
H Lan et al.
DIABETES (2003)
PPAR-γ activation mediates adipose depot-specific effects on gene expression and lipoprotein lipase activity -: Mechanisms for modulation of postprandial lipemia and differential adipose accretion
M Laplante et al.
DIABETES (2003)
The regulation and activation of ciliary neurotrophic factor signaling proteins in adipocytes
S Zvonic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Obesity is associated with macrophage accumulation in adipose tissue
SP Weisberg et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Dissociation of obesity and impaired glucose disposal in mice overexpressing acyl coenzyme A:diacylglycerol acyltransferase 1 in white adipose tissue
HC Chen et al.
DIABETES (2002)
Heterozygous knockout of the IRS-1 gene in mice enhances obesity-linked insulin resistance: a possible model for the development of type 2 diabetes
A Shirakami et al.
JOURNAL OF ENDOCRINOLOGY (2002)
Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARγ agonists
GQ Jiang et al.
DIABETES (2002)
Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance
M Blüher et al.
DEVELOPMENTAL CELL (2002)
Isomer-dependent metabolic effects of conjugated linoleic acid -: Insights from molecular markers sterol regulatory element-binding protein-1c and LXRα
HM Roche et al.
DIABETES (2002)
A method to identify serine kinase substrates - Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain
S Kane et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Euglycemic hyperinsulinemia augments the cytokine and endocrine responses to endotoxin in humans
M Soop et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
Insulin and rosiglitazone regulation of lipolysis and lipogenesis in human adipose tissue in vitro
PG McTernan et al.
DIABETES (2002)
Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle
G Haemmerle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Exclusive action of transmembrane TNFα in adipose tissue leads to reduced adipose mass and local but not systemic insulin resistance
HY Xu et al.
ENDOCRINOLOGY (2002)
Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes
A Stahl et al.
DEVELOPMENTAL CELL (2002)
Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-α
C Sewter et al.
DIABETES (2002)
Mechanism for fatty acid sparing effect on glucose-induced transcription - Regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase
T Kawaguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Sterol regulatory element binding protein 1c (SREBP-1c) expression in human obesity
M Kolehmainen et al.
OBESITY RESEARCH (2001)
Insulin up-regulates tumor necrosis factor-α production in macrophages through an extracellular-regulated kinase-dependent pathway
KT Iida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Adipose tissue and the insulin resistance syndrome
KN Frayn
PROCEEDINGS OF THE NUTRITION SOCIETY (2001)
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
H Yamashita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Insulin inhibits intranuclear nuclear factor κB and stimulates IκB in mononuclear cells in obese subjects:: Evidence for an anti-inflammatory effect?
P Dandona et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2001)
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKBβ)
H Cho et al.
SCIENCE (2001)
Chronic endothelin-1 treatment leads to heterologous desensitization of insulin signaling in 3T3-L1 adipocytes
K Ishibashi et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Regulation by insulin of gene expression in human skeletal muscle and adipose tissue - Evidence for specific defects in type 2 diabetes
PH Ducluzeau et al.
DIABETES (2001)
Rab proteins as membrane organizers
M Zerial et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Absence of perilipin results in leanness and reverses obesity in Lepr db db mice
J Martinez-Botas et al.
NATURE GENETICS (2000)
MAP kinases Erk1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro
G Roth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The expression of adipogenic genes is decreased in obesity and diabetes mellitus
ST Nadler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene
M Amemiya-Kudo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Decreased Akt kinase activity and insulin resistance in C57BL/KsJ-Leprdb/db mice
J Shao et al.
JOURNAL OF ENDOCRINOLOGY (2000)
Impaired phosphorylation and insulin-stimulated translocation to the plasma membrane of protein kinase B/Akt in adipocytes from Type II diabetic subjects
E Carvalho et al.
DIABETOLOGIA (2000)
Natriuretic peptides:: a new lipolytic pathway in human adipocytes
C Sengenès et al.
FASEB JOURNAL (2000)
Insulin resistance in fat cells from obese Zucker rats - Evidence for an impaired activation and translocation of protein kinase B and glucose transporter 4
E Carvalho et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2000)
Share Paper
