Related references
Note: Only part of the references are listed.Cardiac-Specific Overexpression of HIF-1α Prevents Deterioration of Glycolytic Pathway and Cardiac Remodeling in Streptozotocin-Induced Diabetic Mice
Wanli Xue et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Methylglyoxal-induced imbalance in the ratio of vascular endothelial growth factor to angiopoietin 2 secreted by retinal pigment epithelial cells leads to endothelial dysfunction
C. F. Bento et al.
EXPERIMENTAL PHYSIOLOGY (2010)
Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α
Weibo Luo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
High glucose activates HIF-1-mediated signal transduction in glomerular mesangial cells through a carbohydrate response element binding protein
Tsubasa Isoe et al.
KIDNEY INTERNATIONAL (2010)
The Chaperone-Dependent Ubiquitin Ligase CHIP Targets HIF-1α for Degradation in the Presence of Methylglyoxal
Carla Figueira Bento et al.
PLOS ONE (2010)
Association of hypoxia inducible factor-1 alpha gene polymorphism with both type 1 and type 2 diabetes in a Caucasian (Hungarian) sample
Geza Nagy et al.
BMC MEDICAL GENETICS (2009)
The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues
Hariharan Thangarajah et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
Kakali Sarkar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Biology of HIF-1 alpha
A. Weidemann et al.
CELL DEATH AND DIFFERENTIATION (2008)
Decreasing intracellular superoxide corrects defective ischemia-induced new vessel formation in diabetic mice
Daniel J. Ceradini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Age-dependent impairment of HIF-1α expression in diabetic mice:: Correction with electroporation-facilitated gene therapy increases wound healing, angiogenesis, and circulating angiogenic cells
Lixin Liu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Glucose up-regulates HIF-1α expression in primary cortical neurons in response to hypoxia through maintaining cellular redox status
Shuhong Guo et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Hypoxia-Associated Factor, a Novel E3-Ubiquitin Ligase, Binds and Ubiquitinates Hypoxia-Inducible Factor 1α, Leading to Its Oxygen-Independent Degradation
Mei Yee Koh et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Stabilization of HIF-1α is critical to improve wound healing in diabetic mice
Ileana Ruxandra Botusan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Vascular endothelial growth factor and diabetic complications
Barbara Wirostko et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2008)
SUMO-Specific protease 1 is essential for stabilization of HIF1α during hypoxia
Jinke Cheng et al.
CELL (2007)
RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1α during hypoxia
Alberto Carbia-Nagashima et al.
CELL (2007)
SUMOylation of hypoxia-inducible factor-lα reduces its transcriptional activity
Melanie A. Berta et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
The role of hypoxia-inducible factors in cancer
M. A. Maynard et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1α
Katherine A. Gallagher et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Reduction of VEGF-A and CTGF expression in diabetic nephropathy is associated with podocyte loss
H. J. Baelde et al.
KIDNEY INTERNATIONAL (2007)
Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes
Thomas Thum et al.
DIABETES (2007)
Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates
Kirsty S. Hewitson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
RACK1 competes with HSP90 for binding to HIF-1α and is required for O2-independent and HSP90 inhibitor-induced degradation of HIF-1α
Ye V. Liu et al.
MOLECULAR CELL (2007)
Sustained expression of Hif-1 alpha in the diabetic environment promotes angiogenesis and cutaneous wound repair
Kimberly A. Mace et al.
WOUND REPAIR AND REGENERATION (2007)
Diabetes impairs progenitor cell mobilisation after hindlimb ischaemia-reperfusion injury in rats
G. P. Fadini et al.
DIABETOLOGIA (2006)
Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1α
Ilias Mylonis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Altered gene expression related to glomerulogenesis and podocyte structure in early diabetic nephropathy of db/db mice and its restoration by pioglitazone
Hisashi Makino et al.
DIABETES (2006)
Gene transfer of an engineered transcription factor promoting expression of VEGF-A protects against experimental diabetic neuropathy
Sally A. Price et al.
DIABETES (2006)
VEGF 164 gene transfer by electroporation improves diabetic sensory neuropathy in mice
Tatsufumi Murakami et al.
JOURNAL OF GENE MEDICINE (2006)
Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1α
XG Kong et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Genetic variation in the hypoxia-inducible factor-1α gene is associated with type 2 diabetes in Japanese
N Yamada et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
HSV-mediated gene transfer of vascular endothelial growth factor to dorsal root ganglia prevents diabetic neuropathy
M Chattopadhyay et al.
GENE THERAPY (2005)
Loss of ARNT/HIF1β mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes
JE Gunton et al.
CELL (2005)
Hypoxia-inducible factor 1α polymorphism and coronary collaterals in patients with ischemic heart disease
JR Resar et al.
CHEST (2005)
Stromal cell-derived factor-1α and CXCR4 expression in hermangioblastoma and clear cell-renal cell carcinoma:: von Hippe-Lindau loss-of-function induces expression of a ligand and its receptor
D Zagzag et al.
CANCER RESEARCH (2005)
Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy - Restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishment of local vascular endothelial growth factor
YS Yoon et al.
CIRCULATION (2005)
VHLprotein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1α
ZB Li et al.
EMBO REPORTS (2005)
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
MA Selak et al.
CANCER CELL (2005)
Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor
S Linke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Hyperglycemia-induced defects in angiogenesis in the chicken chorioallantoic membrane model
E Larger et al.
DIABETES (2004)
Impairment in ischemia-induced neovascularization in diabetes - Bone marrow mononuclear cell dysfunction and therapeutic potential of placenta growth factor treatment
R Tamarat et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress
K Salnikow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
DJ Ceradini et al.
NATURE MEDICINE (2004)
Hyperglycentia regulates hypoxia-inducible factor-1α protein stability and function
SB Catrina et al.
DIABETES (2004)
Endothelial progenitor cell dysfunction - A novel concept in the pathogenesis of vascular complications of type 1 diabetes
CJM Loomans et al.
DIABETES (2004)
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
A Aicher et al.
NATURE MEDICINE (2003)
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia
E Berra et al.
EMBO JOURNAL (2003)
The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1α by a von Hippel-Lindau protein-independent mechanism
TTL Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice
R Tamarat et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Cobalt inhibits the interaction between hypoxia-inducible factor-α and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-α
Y Yuan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Direct interactions between HIF-1α and Mdm2 modulate p53 function
DL Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
NL Sang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
HIF hydroxylation and the mammalian oxygen-sensing pathway
M Safran et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Human endothelial progenitor exhibit impaired proliferation, cells from type II diabetics adhesion, and incorporation into vascular structures
OM Tepper et al.
CIRCULATION (2002)
Two sequence motifs from HIF-1α bind to the DNA-binding site of p53
LO Hansson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway
C Treins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Myocardial infarction in diabetic rats: role of hyperglycaemia on infarct size and early expression of hypoxia-inducible factor 1
R Marfella et al.
DIABETOLOGIA (2002)
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family
KS Hewitson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Structural basis for the recognition of hydroxyproline in αIF-1α by pVHL
WC Hon et al.
NATURE (2002)
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
D Lando et al.
GENES & DEVELOPMENT (2002)
Susceptibility of glutatione and glutathione-related antioxidant activity to hydrogen peroxide in patients with type 2 diabetes:: effect of glycemic control
Y Dinçer et al.
CLINICAL BIOCHEMISTRY (2002)
Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic states - A possible explanation for impaired collateral formation in cardiac tissue
E Chou et al.
CIRCULATION (2002)
A conserved family of prolyl-4-hydroxylases that modify HIF
RK Bruick et al.
SCIENCE (2001)
FIH-1:: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
PC Mahon et al.
GENES & DEVELOPMENT (2001)
HIFα targeted for VHL-mediated destruction by proline hydroxylation:: Implications for O2 sensing
M Ivan et al.
SCIENCE (2001)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)
Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide
H Kimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Activation of HIF1α ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex
T Kamura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
ME Cockman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Blood-derived angioblasts accelerate blood-flow restoration in diabetic mice
GC Schatteman et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein
M Ohh et al.
NATURE CELL BIOLOGY (2000)