Journal
DIABETES-METABOLISM RESEARCH AND REVIEWS
Volume 28, Issue -, Pages 32-39Publisher
WILEY
DOI: 10.1002/dmrr.2352
Keywords
type 2 diabetes; prevalence; risk factors
Categories
Funding
- Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health [1994DP131044]
- Sector Funds of Ministry of Health [201002002]
- National Key New Drug Creation and Manufacturing Program of Ministry of Science and Technology [2012ZX09303006-001]
- National Natural Science Foundation of China [81222008, 81100564, 30911120493, 81130016]
- New One Hundred Person Project of Shanghai Jiao-Tong University School of Medicine
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The prevalence of type 2 diabetes is increasing globally and poses a heavy burden on public health and socioeconomic development of all nations. Type 2 diabetes is a multifactorial disease and due to a combination of environmental and genetic risk factors. Many environmental risk factors contribute to the pathogenesis of type 2 diabetes, including lifestyles such as sedentary behaviour, diet, smoking and alcohol consumption, internal environmental factors such as inflammatory factors, adipocytokines and hepatocyte factors, external environmental factors such as environmental endocrine disruptors. This review summarizes current research efforts concentrated on the contributors for accelerated type 2 diabetes epidemic. It also provides a novel prospect for future researches.
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