Weight loss in obese patients with type 2 diabetes: Effects of telemonitoring plus a diet combination - The Active Body Control (ABC) Program

Aims: We evaluate the efficacy of the Active Body Control (ABC) Program'' for weight reduction in patients with type 2 diabetes. Methods: The ABC program combines telemonitoring of the physical activity with a low-calorie diet also preferring carbohydrates with low glycemic indexes. In this 6-month, randomized, clinical trial 35 patients (aged 57 +/- 9 years; BMI = 35.3 +/- 5.7 kg/m(2)) were treated according to the ABC program and 35 control patients (aged 58 +/- 7 years; BMI = 34.8 +/- 5.9 kg/m(2)) received standard therapy. Results: After 6 months the mean weight loss in the intervention group was 11.8 kg +/- 8.0 kg. Glucose and HbA1c were lowered by respectively 1.0 mmol/l and 0.8 percentage points (p = 0.000, respectively). The proportion of patients with HbA1c > 7% fell from 57% to 26%. Antidiabetic drugs were discontinued in 13 patients (39%) and reduced in 14 (42%). The reduction of costs on medication per patient was (sic)83 in 6 months. In the control group, there were no relevant changes in body weight, laboratory values or drug treatment. Conclusions: The ABC program effectively lowers body weight, Hb1Ac and antidiabetic drug use in patients with type 2 diabetes. (C) 2010 Elsevier Ireland Ltd. All rights reserved.