Journal
DIABETES CARE
Volume 36, Issue 6, Pages 1604-1606Publisher
AMER DIABETES ASSOC
DOI: 10.2337/dc12-1102
Keywords
-
Categories
Funding
- Office of Research and Development
- Health Services Research and Development
- U.S. Department of Veterans Affairs [TPP 61-026, RCS 98-353]
Ask authors/readers for more resources
OBJECTIVE-To determine whether diabetes status, including prediabetes, is associated with increased risk of peripheral neuropathy as defined by monofilament insensitivity. RESEARCH DESIGN AND METHODS-This study used data from the 1999-2004 National Health and Nutrition Examination Survey (n = 7,818). Peripheral neuropathy was defined as one or more insensate sites detected by a Semmes-Weinstein 10-g monofilament. Generalized linear models were used to directly estimate relative risks (RRs) for the association of diabetes status and peripheral neuropathy. RESULTS-After adjustment compared with no diabetes, prediabetes [RR 1.11(95% CI 0.92-1.34)] and undiagnosed diabetes [1.08 (0.73-1.61)] were associated with modest increases in risk of peripheral neuropathy, and diabetes was associated with a 74% higher risk of peripheral neuropathy [1.74 (1.50-2.01)]. CONCLUSIONS-Diabetes is associated with increased risk of peripheral neuropathy defined by monofilament insensitivity, but prediabetes and undiagnosed diabetes may be associated with only a modest increase in risk.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available