Prevention of Diabetes Self-Management Program (PREDIAS): Effects on Weight, Metabolic Risk Factors, and Behavioral Outcomes

OBJECTIVE - To evaluate the efficacy Of the group program PREDIAS for diabetes prevention. RESEARCH DESIGN AND METHODS - PREDIAS consists Of 12 lessons and aims at lifestyle modification. The control group received written information about diabetes prevention. In this Study, a total of 182 persons with an elevated diabetes risk participated (aged 56.3 +/- 10.1 years, 43% female, and BMI 31.5 +/- 5.3 kg/m(2)). RESULTS - After 12 months, weight loss was significantly higher (P = 0.001) in PREDIAS than in the control group (-3.8 +/- 5.2 vs. -1.4 +/- 4.09 kg). There were also significant effects (P = 0.001) on fasting glucose (control group 1.8 +/- 13.1 mg/dl vs. PREDIAS -4.3 +/- 11.3 mg/dl), duration of physical activity per week (control group 17.9 +/- 63.8 min vs. PREDIAS 46.6 +/- 95.5 min; P = 0.03), and eating behavior. CONCLUSIONS - PREDIAS significantly modified lifestyle factors associated With an elevated diabetes risk.