Journal
DIABETES & METABOLISM
Volume 34, Issue 5, Pages 447-454Publisher
MASSON EDITEUR
DOI: 10.1016/j.diabet.2008.08.001
Keywords
Metabolic syndrome; Diabetes mellitus; Lung dysfunction; Obstructive sleep apnoea (OSA); Chronic obstructive pulmonary disease (COPD); Endothelial progenitor cells (EPC); Review
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Sleep-disordered breathing and sleep apnoea are conditions frequently associated with comorbidity, including obesity, diabetes, hypertension, insulin resistance (metabolic syndrome) and cardiovascular disease. The diabetic state (type 1 and type 2 diabetes) may be associated to diminished lung function and, in particular, decreased vital capacity, and the association between chronic obstructive pulmonary disease (COPD) and type 2 diabetes may be due to a shared inflammatory process. Also, the alteration in circulating endothelial progenitor cells found in respiratory disease, the metabolic syndrome and cardiovascular disease reflect a common condition of endothelial dysfunction. (C) 2008 Elsevier Masson SAS. All rights reserved.
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