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Animal Models of Early Life Stress: Implications for Understanding Resilience

Journal

DEVELOPMENTAL PSYCHOBIOLOGY
Volume 52, Issue 5, Pages 402-410

Publisher

WILEY
DOI: 10.1002/dev.20429

Keywords

emotion regulation; cognitive control; prefrontal plasticity; HPA axis; curiosity; anxiety; cortisol; squirrel monkey

Funding

  1. Public Health Service [MH47573, MH66537, MH77884, DA16902]

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In the mid-1950s, Levine and his colleagues reported that brief intermittent exposure to early life stress diminished indications of subsequent emotionality in rats. Here we review ongoing studies of a similar process in squirrel monkeys. Results from these animal models suggest that brief intermittent exposure to stress promotes the development of arousal regulation and resilience. Implications for programs designed to enhance resilience in human development are discussed. (C) 2010 Wiley Periodicals, Inc. Dev Psychobiol 52: 402-410, 2010.

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