Journal
DEVELOPMENTAL DYNAMICS
Volume 239, Issue 4, Pages 1234-1245Publisher
WILEY
DOI: 10.1002/dvdy.22264
Keywords
chick; Pbx; Meis; Prep; Tgif; embryo; gene expression
Categories
Funding
- European Commission [LSHM-CT-2003-504468]
- BBSRC
- MRC [G0500826] Funding Source: UKRI
- Medical Research Council [G0500826] Funding Source: researchfish
Ask authors/readers for more resources
The TALE family of homeodomain containing transcription factors consists of the Meis, Prep and Tgif, and the Pbx subfamily of proteins. Several TALE orthologues have been identified in amniotes, but no comprehensive analysis of their expression pattern during embryogenesis has been performed. Here, we report on TALE gene expression in the avian embryo. During embryonic development, Pbx genes are predominantly expressed in the neural ectoderm and paraxial mesoderm, although Pbx3 is restricted to the intermediate and lateral mesoderm, and anterior central nervous system. Members of the Meis, Prep, and Tgif subfamilies are expressed at high levels in the paraxial mesoderm, and display differential expression along the anterior posterior and dorsoventral axes of the developing neural tube. Overall the expression patterns reported in this study are consistent with the known function of the TALE gene family in controlling early patterning of limb, neural tube and paraxial mesoderm tissues during embryogenesis. Developmental Dynamics 239:1234-1245, 2010. (C) 2010 Wiley-Liss, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available