Journal
DEVELOPMENTAL CELL
Volume 31, Issue 2, Pages 139-140Publisher
CELL PRESS
DOI: 10.1016/j.devcel.2014.10.010
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Funding
- NHLBI NIH HHS [R01 HL094414] Funding Source: Medline
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Microtubules can target proteins such as Connexin43 to plasma membrane subdomains. Patel et al. (2014) now show that the structural desmosome complex participates in targeted trafficking of membrane components through interactions between the microtubule network and the N terminus of desmoplakin, a region that is a pathogenic mutation hotspot.
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