Journal
DEVELOPMENTAL CELL
Volume 27, Issue 1, Pages 1-2Publisher
CELL PRESS
DOI: 10.1016/j.devcel.2013.09.027
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Funding
- NIGMS NIH HHS [R01 GM056312, R01 GM106023, R01-GM056312, R01-GM106023] Funding Source: Medline
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How nuclear morphology is regulated during development and disease remains poorly understood. In this issue of Developmental Cell, using a pronuclear assembly assay, Xue et al. (2013) demonstrate that Dppa2, a chromatin-bound microtubule regulator, controls both the morphology and function of the pronucleus by fine-tuning microtubule dynamics.
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