4.7 Editorial Material

A Chromatin Switch for Chromosome Condensation

Journal

DEVELOPMENTAL CELL
Volume 23, Issue 6, Pages 1127-1128

Publisher

CELL PRESS
DOI: 10.1016/j.devcel.2012.11.016

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Funding

  1. CIHR [87253-1, 64289-3, 14308-4] Funding Source: Medline

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Reporting in Molecular Cell, Tanaka et al. (2012) show that the Ku heterodimer recruits the condensin complex for retrotransposon clustering in Schizosacchromyces pombe. Histone H3 acetylation on lysine 56 blocks Ku binding and modulates this regulation of genome organization during the cell cycle and in response to DNA damage.

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