4.7 Editorial Material

Eliminating Mitochondrial DNA from Sperm

Journal

DEVELOPMENTAL CELL
Volume 22, Issue 3, Pages 469-470

Publisher

CELL PRESS
DOI: 10.1016/j.devcel.2012.02.008

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Funding

  1. Howard Hughes Medical Institute Funding Source: Medline
  2. NIGMS NIH HHS [R01 GM062967, R01 GM083121] Funding Source: Medline

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Most eukaryotes show uniparental inheritance of mitochondrial DNA (mtDNA). In this issue of Developmental Cell, DeLuca and O'Farrell (2012) show that active elimination of mtDNA during sperm development in Drosophila ensures that mature spermatozoa are devoid of DNA.

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