4.7 Editorial Material

Enhancers: From Developmental Genetics to the Genetics of Common Human Disease

Journal

DEVELOPMENTAL CELL
Volume 21, Issue 1, Pages 17-19

Publisher

CELL PRESS
DOI: 10.1016/j.devcel.2011.06.008

Keywords

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Funding

  1. MRC [MC_PC_U127584494, MC_U127527202, MC_U127584494] Funding Source: UKRI
  2. Medical Research Council [MC_U127584494, MC_PC_U127584494, MC_U127527202] Funding Source: researchfish
  3. Medical Research Council [MC_U127527202, MC_U127584494, MC_PC_U127584494] Funding Source: Medline

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In mammals, long-range gene regulation became apparent through simple Mendelian disease genetics in human and developmental genetics in the mouse. Can the insights into gene control, provided by the study of these enhancers, help us understand the functional significance of sequence variation associated with common/complex human disease and quantitative traits?

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