4.7 Editorial Material

Can a Systems Perspective Help Us Appreciate the Biological Meaning of Small Effects?

Journal

DEVELOPMENTAL CELL
Volume 21, Issue 1, Pages 11-13

Publisher

CELL PRESS
DOI: 10.1016/j.devcel.2011.06.005

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Funding

  1. NIGMS NIH HHS [R01 GM086379] Funding Source: Medline

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The study of dramatic phenotypes has been pivotal to elucidating biological mechanisms. Effectively approaching low-magnitude quantitative phenotypes, a common outcome of systematic loss-of-function studies, will be critical for understanding how individual components of cells interact to generate functioning systems.

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