Journal
DEVELOPMENTAL CELL
Volume 20, Issue 5, Pages 578-580Publisher
CELL PRESS
DOI: 10.1016/j.devcel.2011.05.002
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An interplay between intrinsic polarity and extracellular cues guides neuronal migration during cerebellar development. In this issue of Developmental Cell, Zhou et al. (2011) demonstrate that Numb is the focal point in mediating the chemotactic response of migrating cerebellar granule cells to BDNF through its regulation of cell polarity.
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