Journal
DEVELOPMENTAL BIOLOGY
Volume 373, Issue 2, Pages 235-243Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ydbio.2012.10.031
Keywords
Kruppel-like factor; Adipocyte; Adipogenesis; Transcription
Categories
Funding
- National Science Fundation of China [30972463, 81172664]
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The zinc-finger transcription factors of the kruppel-like factor family (KLF) are critical in many physiological and pathological processes including cell proliferation, differentiation, inflammation, and apoptosis. Recently, there is increasing evidence that suggests these KLFs have an important role in fat biology. This review summarizes the role of KLFs in lipid metabolism, especially in adipogenesis, and reveals the relationship networks among members of KLF family in differentiation. (C) 2012 Elsevier Inc. All rights reserved.
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