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Embryonic stem cell strategies to explore neural crest development in human embryos

Journal

DEVELOPMENTAL BIOLOGY
Volume 366, Issue 1, Pages 96-99

Publisher

ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ydbio.2012.01.016

Keywords

Neural crest; Human embryonic stem cells; In vitro culture

Funding

  1. Agence Nationale pour la Recherche (ANR)
  2. Association pour la Recherche contre le Cancer [SFI20101201882]
  3. CNRS
  4. Universite Paris Sud
  5. DIM Stem Pole/Region Ile-de-France

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Controling embryonic stem cell fate in vitro has been a major challenge in the past decade. Several protocols have been developed to obtain neural crest derivatives in culture, using more or less defined conditions. Here, we present various strategies used to date to obtain neural crest specification and the markers that can be used to identify human neural crest cells. (C) 2012 Elsevier Inc. All rights reserved.

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