Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 80, Issue 11, Pages 5984-5991Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b00785
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Funding
- National Natural Science Foundation of China [21272085, 21472056]
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A highly efficient I-2-catalyzed Povarov-type reaction of methyl ketones, arylamines, and alpha-ketoesters is developed. This reaction utilizes a catalytic amount of HI coproduct as a promoter for the synthesis of substituted quinolones. This Simple procedure represents an interesting new form of reactivity for the Povarov reaction with good functional group compatibility.
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