Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 80, Issue 22, Pages 11544-11550Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b01713
Keywords
-
Categories
Funding
- CSIR, New Delhi
- DST, New Delhi [SR/S1/OC-42/2010]
Ask authors/readers for more resources
An efficient annulation strategy involving the reaction of phenolic acetates with acrylates in the presence of [Rh-2(OAc)(4)] as catalyst and formic acid as reducing agent, leading to the high yield synthesis of coumarin derivatives, has been developed. The addition of NaOAc as a base increased the yield of the products. The reaction is quite Successful for both electron rich as well as electron deficient phenolic acetates, affording coumarins with excellent regioselectivity, and proceeds via, C-H bond activation proven by deuterium incorporation studies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available