Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 80, Issue 21, Pages 11092-11099Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b01696
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Funding
- National Research Foundation of Korea (NRF) - Korea Government [2013R1A2A2A01005249, 2013R1A1A2058800]
- National Research Foundation of Korea [2013R1A1A2058800] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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The rhodium(III)-catalyzed site-selective C-H alkylation of various N-heterocycles, such as indolines, carbazoles, and pyrroles with readily available allylic alcohols is described. This protocol allows the generation of a heterocyclic scaffold containing a beta-aryl carbonyl moiety, which is known to be a crucial structural unit of biologically active compounds.
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