Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 80, Issue 14, Pages 7251-7257Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b00800
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- Jiangsu University [1281290006]
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Coumarin and flavone derivatives are highly valuable molecules in drug discovery. Here, two new regioselective cross-dehydrogenation couplings of coumarins and flavones with different ethers via C(sp(3))-H functionalization processes were developed, generating new ether-substituted derivatives not previously reported. These reactions proceeded well via radical mechanisms and provided the corresponding products in good yields.
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