Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 80, Issue 14, Pages 7226-7234Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b01227
Keywords
-
Categories
Funding
- Universita dell'Insubria
- Ministero dell'Universita e della Ricerca [PRIN 2012C5YJSK_001]
Ask authors/readers for more resources
A highly effective synthesis of haloalkylidene-substituted heterocycles by copper(II)-catalyzed cyclization of alkynyl ureas and secondary amides has been developed. The reaction, which involves a catalytic amount of CuCl2 and a stoichiometric amount of N-halosuccinimide, occurs selectively through an alkoxyhalogenation process. Alternatively, alkoxychlorination and alkoxybromination reactions can be performed working solely with stoichiometric CuCl, and CuBr2, respectively.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available