Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 80, Issue 22, Pages 11529-11537Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b01324
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Funding
- Swedish Research Council (VR)
- Stiftelsen Olle Engkvist Byggmastare
- Swedish Energy Agency
- Knut and Alice Wallenberg Foundation
- Swedish Government Agency for Innovation Systems (VINNOVA) through the Berzelii Center EXSELLENT on porous Materials
- SYNFLOW
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N-Heterocyclic carbene phosphine iridium complexes (NHC-Ir) were developed/found to be a highly reactive catalyst for N-monoalkylation of amides with alcohols via hydrogen transfer. The reaction produced the desired product in high isolated yields using a wide range of substrates with low catalyst loading and short reaction times.
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