Palladacycle-Catalyzed Carbonylative Suzuki-Miyaura Coupling with High Turnover Number and Turnover Frequency

This work reports the carbonylative Suzuki Miyaura coupling of aryl iodides catalyzed by- palladacydes. More importantly, the palladacydes have been used to generate high turnover numbers (TON's) and turnover frequencies (TOF's). A range of aryl iodides can be coupled with arylboronic acids, generating TON's in the range of 106 to 10 and TOF's in the range of 10(5) to 10(6) Comparison of the palladacydes with a conventional palladium source shows their superiority in generating high TON's and TOF's.